| Names | |
|---|---|
| IUPAC name | |
Other names
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| Identifiers | |
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| ChEMBL | |
| ChemSpider |
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| ECHA InfoCard | 100.002.201 |
| EC Number | |
PubChemCID | |
| RTECS number |
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| UNII | |
CompTox Dashboard(EPA) | |
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| Properties | |
| C4H8N2O2 | |
| Molar mass | 116.120 g·mol−1 |
| Appearance | White/Off White Powder |
| Density | 1.37 g/cm3 |
| Melting point | 240 to 241 °C (464 to 466 °F; 513 to 514 K) |
| Boiling point | decomposes |
| low | |
| Structure | |
| 0 | |
| Hazards | |
| Main hazards | Toxic, Skin/Eye Irritant |
| Safety data sheet | External MSDS |
| GHS pictograms | |
| GHS Signal word | Danger |
| H228, H301 | |
| P210, P240, P241, P264, P270, P280, P301+310, P321, P330, P370+378, P405, P501 | |
| NFPA 704 (fire diamond) | |
| Related compounds | |
| Hydroxylamine salicylaldoxime | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| verify (what is ?) | |
| Infobox references | |
Dimethylglyoxime is a chemical compound described by the formula CH3C(NOH)C(NOH)CH3. Its abbreviation is dmgH2 for neutral form, and dmgH for anionic form, where H stands for hydrogen. This colourless solid is the dioxime derivative of the diketone butane-2,3-dione (also known as diacetyl). DmgH2 is used in the analysis of palladium or nickel. Its coordination complexes are of theoretical interest as models for enzymes and as catalysts. Many related ligands can be prepared from other diketones, e.g. benzil.
Apr 02, 2010 what is the molar mass (g/mol) of the protein? 24.0 mg of a certain protein was dissolved in water to make a solution of 4.50 mL at 21.0 oC. If the osmotic pressure is 1.15 torr, what is the molar mass (g/mol) of the protein? Jan 14, 2019 The molar mass of glucose can be calculated by multiplying the molar masses of its atomic constituents by their frequency in a single molecule, and adding those values together. Glucose is composed of hydrogen (H), carbon (C), and oxygen (O) The molar mass of H is 1.0079, the molar mass of C is 12.0107. The molar mass of a substance is the weight of 6.02 × 10 23 atoms or molecules of that material in grams. The unit of molar mass is given as grams/mole, usually abbreviated as g/mol. As a result, we're going to have to learn to find something called the molar mass—the weight of one mole of a chemical compound. That way, if somebody says that. Jan 14, 2019 The molar mass of glucose can be calculated by multiplying the molar masses of its atomic constituents by their frequency in a single molecule, and adding those values together. Glucose is composed of hydrogen (H), carbon (C), and oxygen (O) The molar mass of H is 1.0079, the molar mass. Dimethylglyoxime, DMG, is an organic compound used to test for aqueous nickel(II) ions. A solution prepared by dissolving 65.0 g of DMG in 375 g of ethanol boils at 80.3°C. What is the molar mass of DMG? Kb = 1.22°C/m, boiling point of pure ethanol = 78.5°C.
Preparation[edit]
Dimethylglyoxime can be prepared from butanone first by reaction with ethyl nitrite to give biacetyl monoxime. The second oxime is installed using sodium hydroxylamine monosulfonate:[1]
Complexes[edit]
Dimethylglyoxime is used to detect and quantify nickel, which forms the bright red complex nickel bis(dimethylglyoximate) (Ni(dmgH)2). The reaction was discovered by L. A. Chugaev in 1905.[2]
Cobalt complexes have also received much attention. In chloro(pyridine)cobaloxime[3] the macrocycle [dmgH]22− mimics the macrocyclic ligand found in vitamin B12.
References[edit]
- ^Semon, W. L.; Damerell, V. R. (1930). 'Dimethylglyoxime'. Organic Syntheses. 10: 22. doi:10.15227/orgsyn.010.0022.CS1 maint: multiple names: authors list (link)
- ^Lev Tschugaeff (1905). 'Über ein neues, empfindliches Reagens auf Nickel'. Berichte der Deutschen Chemischen Gesellschaft. 38 (3): 2520–2522. doi:10.1002/cber.19050380317.
- ^Girolami, G.. S.; Rauchfuss, T.B.; Angelici, R. J. (1999). Synthesis and Technique in Inorganic Chemistry: A Laboratory Manual (3rd ed.). pp. 213–215.
| Names | |
|---|---|
| IUPAC name | |
| Other names N,N-Dimethylglycine | |
| Identifiers | |
| |
| 3DMet | |
| 1700261 | |
| ChEBI | |
| ChemSpider |
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| DrugBank | |
| ECHA InfoCard | 100.012.971 |
| EC Number |
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| 82215 | |
| KEGG |
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| MeSH | dimethylglycine |
| RTECS number | |
CompTox Dashboard(EPA) | |
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| |
| Properties | |
| C4H9NO2 | |
| Molar mass | 103.121 g·mol−1 |
| Appearance | White crystals |
| Odor | Odourless |
| Density | 1.069 g/mL |
| Melting point | 178 to 182 °C (352 to 360 °F; 451 to 455 K) |
| Boiling point | 175.2 °C (347.4 °F; 448.3 K) |
| Hazards | |
| GHS pictograms | |
| GHS Signal word | Warning |
| H302 | |
| Lethal dose or concentration (LD, LC): | |
| >650 mg kg−1(oral, rat) | |
| Related compounds | |
Related alkanoic acids | |
| Dimethylacetamide | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| verify (what is ?) | |
| Infobox references | |
Dimethylglycine (DMG) is a derivative of the amino acidglycine with the structural formula (CH3)2NCH2COOH. It can be found in beans and liver. It can be formed from trimethylglycine upon the loss of one of its methyl groups. It is also a byproduct of the metabolism of choline.
When DMG was first discovered, it was referred to as Vitamin B16, but, unlike true B vitamins, deficiency of DMG in the diet does not lead to any ill-effects and it is synthesized by the human body in the citric acid (or Krebs) cycle meaning it does not meet the definition of a vitamin.
Uses[edit]
Dimethylglycine has been suggested for use as an athletic performance enhancer, immunostimulant, and a treatment for autism, epilepsy, or mitochondrial disease.[2] There is no evidence that dimethylglycine is effective for treating mitochondrial disease.[3] Published studies on the subject have shown little to no difference between DMG treatment and placebo in autism spectrum disorders.[4][5]
Biological activity[edit]
Dimethylglycine has been found to act as an agonist of the glycine site of the NMDA receptor.[6]
Preparation[edit]
This compound is commercially available as the free form amino acid, and as the hydrochloride salt [2491-06-7 ]. DMG may be prepared by the alkylation of glycine via the Eschweiler–Clarke reaction. In this reaction, glycine is treated with aqueous formaldehyde in formic acid that serves as both solvent and reductant. Hydrochloric acid is added thereafter to give the hydrochloride salt. The free amino acid may have been obtained by neutralization of the acid salt, which has been performed with silver oxide.[7]
- H2NCH2COOH + 2 CH2O + 2 HCOOH → (CH3)2NCH2COOH + 2 CO2 + 2 H2O
References[edit]
What Is The Molar Mass Of Dmg 2
- ^'dimethylglycine - Compound Summary'. PubChem Compound. USA: National Center for Biotechnology Information. 16 September 2004. Identification. Retrieved 24 April 2012.
- ^'Dimethylglycine'. About Herbs, Botanicals & Other Products. Memorial Sloan–Kettering Cancer Center. December 8, 2009.
- ^Pfeffer, Gerald; Majamaa, Kari; Turnbull, Douglass M.; Thorburn, David; Chinnery, Patrick F. (2012-04-18). 'Treatment for mitochondrial disorders'. The Cochrane Database of Systematic Reviews (4): CD004426. doi:10.1002/14651858.CD004426.pub3. ISSN1469-493X. PMID22513923.
- ^Bolman WM, Richmond JA (June 1999). 'A double-blind, placebo-controlled, crossover pilot trial of low-dose dimethylglycine in patients with autistic disorder'. Journal of Autism and Developmental Disorders. 29 (3): 191–4. doi:10.1023/A:1023023820671. PMID10425581.
- ^Kern JK, Miller VS, Cauller PL, Kendall PR, Mehta PJ, Dodd M (March 2001). 'Effectiveness of N,N-dimethylglycine in autism and pervasive developmental disorder'. Journal of Child Neurology. 16 (3): 169–73. doi:10.1177/088307380101600303. PMID11305684.
- ^Lin, Jen-Cheng; Chan, Ming-Huan; Lee, Mei-Yi; Chen, Yi-Chyan; Chen, Hwei-Hsien (2016). 'N,N-dimethylglycine differentially modulates psychotomimetic and antidepressant-like effects of ketamine in mice'. Progress in Neuro-Psychopharmacology and Biological Psychiatry. 71: 7–13. doi:10.1016/j.pnpbp.2016.06.002. ISSN0278-5846. PMID27296677.
- ^Clarke, H. T.; Gillespie, H. B.; Weisshaus, S. Z. (1933). 'The Action of Formaldehyde on Amines and Amino Acids'. Journal of the American Chemical Society. 55 (11): 4571. doi:10.1021/ja01338a041.
What Is The Molar Mass Of Mgf2
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